Periodontopathogens interfere with the human renin-angiotensin system through a surface-attached protease
Irena Waligórska, Krzysztof M. Żak, Natalia Mikrut, Joanna Budziaszek, Volodymyr V. Medviediev, Ewa Bielecka, Tomasz Kantyka, Joanna Kozieł, Ida B. Thøgersen, Jan J. Enghild, Przemysław Grudnik, Jan Potempa, Mirosław Książęk
This study shows that oral pathogens Porphyromonas gingivalis and Tannerella forsythia use surface-attached proteases to alter the renin-angiotensin system by generating Ang 1-7.
Scientific Reports · Nov 27, 2025Peer-reviewedMicrobiology