TXNDC15 modulated quality control at the endoplasmic reticulum shapes ciliogenesis
Vy N. Nguyen, Lena A. K. Bögeholz, Katharine R. Page, Jichen Zhang, Melanie Ernst, T Y Wang, Natalie Chen, Adarsh K. Mayank, Maxine L. Wang, James Wohlschlegel, Tsui‐Fen Chou, Alina Guna, R.M. Voorhees
The paper identifies TXNDC15 as a regulator of ER membrane protein quality control, showing its dual role in modulating MARCHF6 activity and its link to ciliogenesis defects in Meckel-Gruber syndrome.
bioRxiv · Apr 2, 2026 · PreprintMolecular Biology