NPP-21/TPR is required for developmental control of spindle checkpoint strength in C. elegans
Natalie Gallagher, Shevelle Brown, Valentin Duprat, Simone Köhler, Abby F. Dernburg, Needhi Bhalla
This study shows NPP-21/TPR is required for stronger spindle checkpoint in C. elegans germline cells through mechanisms involving PCH-2 concentration and Mad2 localization.
bioRxiv · Apr 24, 2026 · PreprintCell Biology