Author

Needhi Bhalla

University of California, Santa CruzORCID 0000-0002-6859-0073Unclaimed ORCID profile · follow to get notified of new preprints

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Needhi Bhalla2 papers

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Abby F. DernburgiD· 1 shared Alberto Herrera· 1 shared Bhumil Patel· 1 shared Elias Logari· 1 shared Maryke Grobler· 1 shared Natalie Gallagher· 1 shared Shevelle Brown· 1 shared Simone KöhleriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Abby F. DernburgORCID

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2 papers

Recent·Most cited

NPP-21/TPR is required for developmental control of spindle checkpoint strength in C. elegans

Natalie Gallagher, Shevelle Brown, Valentin Duprat, Simone Köhler, Abby F. Dernburg, Needhi Bhalla

This study shows NPP-21/TPR is required for stronger spindle checkpoint in C. elegans germline cells through mechanisms involving PCH-2 concentration and Mad2 localization.

bioRxiv · Apr 24, 2026 · PreprintCell Biology

The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing their formation in C. elegans

Bhumil Patel, Maryke Grobler, Alberto Herrera, Elias Logari, Valery Ortiz, Needhi Bhalla

This study shows that PCH-2 antagonizes crossover formation in C. elegans meiosis, controlling crossover number and distribution through interactions with HORMADs.

eLife · Feb 18, 2025Peer-reviewedCell Biology