Intratumoral B7H3:CD3 Bispecific T-cell Engager Drives Localized T-cell Accumulation in Canine Sarcoma Patients
Yusuke Suita, Lisa S. Ang, Kenneth Brasel, Shelli M. Morris, Emily J. Girard, Alison M. Williams, Steven C. Chen, Ian Blumenthal, Natasha M. Hottmann, Jennifer Heusser, Drew J. Mhyre, Cole A. DeForest, Peter F. Moore, Jason P. Price, Janean L. Fidel, James M. Olson
This study evaluates an intratumoral B7H3:CD3 TCE in canine sarcoma patients, showing localized T-cell accumulation without systemic toxicity.
bioRxiv · May 31, 2026 · PreprintImmunology