Author

Kenneth Brasel

Seattle Children's Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Emily J. GirardiD· 2 shared James M. OlsoniD· 2 shared Shelli M. MorrisiD· 2 shared Alison M. Williams· 1 shared Andrew BondociD· 1 shared Annie HuangiD· 1 shared Augusto Faria AndradeiD· 1 shared Banlanjo Abdulaziz UmaruiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Emily J. GirardORCID

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2 papers

Recent·Most cited

Intratumoral B7H3:CD3 Bispecific T-cell Engager Drives Localized T-cell Accumulation in Canine Sarcoma Patients

Yusuke Suita, Lisa S. Ang, Kenneth Brasel, Shelli M. Morris, Emily J. Girard, Alison M. Williams, Steven C. Chen, Ian Blumenthal, Natasha M. Hottmann, Jennifer Heusser, Drew J. Mhyre, Cole A. DeForest, Peter F. Moore, Jason P. Price, Janean L. Fidel, James M. Olson

This study evaluates an intratumoral B7H3:CD3 TCE in canine sarcoma patients, showing localized T-cell accumulation without systemic toxicity.

bioRxiv · May 31, 2026 · PreprintImmunology

Efficacy of DNA Methyltransferase Inhibitor Immune Priming Therapy in Combination with PD-1 Inhibitors to Treat High-Risk Pediatric Brain Tumors

Deepak Kumar Mishra, Shelli M. Morris, Dean Popovski, Emily J. Girard, Andrew Bondoc, Shiva Senthil Kumar, Augusto Faria Andrade, Xiaoting Zhu, Fupan Yao, Mi‐Youn Brusniak, Banlanjo Abdulaziz Umaru, Erin E. Crotty, Kenneth Brasel, Fiona J. Pakiam, Caterina Russo, , Rachid Drissi

This study investigates the combination of DNA methyltransferase inhibitor decitabine and PD-1 inhibitor in high-risk pediatric brain tumor models, finding improved survival in some subtypes.

bioRxiv · May 14, 2025 · PreprintImmunology