Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
Wei Q. Deng, Nathan Cawte, Natalie Campbell, Sandi M. Azab, Russell J. de Souza, Amel Lamri, Katherine Mary Morrison, Stephanie A. Atkinson, Padmaja Subbarao, Stuart E. Turvey, Theo J. Moraes, Koon Kang Teo, Piush J. Mandhane, Meghan B. Azad, Elinor Simons, , Sonia Savitri Anand
The paper develops a DNA methylation score to quantify the impact of maternal smoking on newborn health outcomes in European and South Asian populations, finding consistent associations with smaller birth size and lower birth weight.
eLife · Jul 24, 2024Peer-reviewedGenetic & Genomic Medicine