Late induction of IgG4 following SARS-CoV-2 mRNA vaccination in pregnant and non-pregnant individuals includes clonotypes raised early in the response
Dhvanir N. Kansara, Tae-Geun Yu, Neel Kansara, Noor M Taher, Aisha Yesbolatova, Larissa DeBrabandere, Joshua A. Weiner, Gabriela Kovacikova, Andrew P. Hederman, Pieter Pannus, Stéphanie Depickère, Maria E Goosens, An Vercoutere, Nicolás Dauby, Kevin K. Ariën, , Margaret E. Ackerman
This study examines how pregnancy affects humoral immunity after SARS-CoV-2 mRNA vaccination, finding delayed IgG4 induction and clonotype characteristics associated with pregnancy.
bioRxiv · May 29, 2026 · PreprintImmunology