Convergent strategies for nanobody-mediated inhibition of an epoxide hydrolase
Adam R. Simard, Noor M Taher, Kathryn S. Beauchemin, Akaash Kumar Mishra, Andrew P. Hederman, Thomas H. Hampton, Natalia Vasylieva, Christophe H.P. Morisseau, Margaret E. Ackerman, Dean R. Madden
The paper identifies two classes of nanobodies that inhibit Cif, an epoxide hydrolase from Pseudomonas aeruginosa, through distinct structural strategies targeting a shared epitope.
Journal of Structural Biology X · Sep 30, 2026Peer-reviewedBiochemistry