GeneticsHuman Molecular GeneticsPeer-reviewed
Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally
Joke Mertens, Marius Regin, Neelke De Munck…·Claudia Spits
The paper shows that mtDNA mosaicism arises early in human preimplantation development and persists into adulthood through asymmetric mitochondrial distribution.
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