Cancer BiologyJournal for ImmunoTherapy of CancerPeer-reviewed
Overcoming impaired antigen presentation in tumor draining lymph nodes facilitates immunotherapy
Meghan J. O’Melia, Lutz Menzel, Pin‐Ji Lei…·Lance L. Munn
This study shows that breast tumors impair antigen presentation in local lymph nodes, which can be overcome by delivering IL1β or adjuvants to distant lymph nodes, improving anti-cancer immune responses.
4 citations