Author

Johanna J. Rajotte

Massachusetts General HospitalORCID 0009-0001-8764-2350Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

James W. BaishiD· 2 shared Lingshan LiuiD· 2 shared Meghan J. O’MeliaiD· 2 shared Timothy P. PaderaiD· 2 shared Brian J. Kinsman· 1 shared Dhruv SinghaliD· 1 shared Genevieve Marie BolandiD· 1 shared Hengbo ZhouiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPhysiology

James W. BaishORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintDec 17, 2025

Selective Activation of NaV1.3 Restores Lymphatic Contractility in Age and Injury

Katarina J. Ruscic, Reetu Singh, Lingshan Liu…·Timothy P. Padera

This study identifies NaV1.3 as a druggable target in adult lymphatic muscle that can restore contractility in aging and radiation injury.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyJournal for ImmunoTherapy of CancerPeer-reviewedDec 1, 2025

Overcoming impaired antigen presentation in tumor draining lymph nodes facilitates immunotherapy

Meghan J. O’Melia, Lutz Menzel, Pin‐Ji Lei…·Lance L. Munn

This study shows that breast tumors impair antigen presentation in local lymph nodes, which can be overcome by delivering IL1β or adjuvants to distant lymph nodes, improving anti-cancer immune responses.

4 citations

humanproteomics

𝕏 PostBluesky