Inactivation of histone chaperone HIRA unmasks a link between normal embryonic development of melanoblasts and maintenance of adult melanocyte stem cells
Farah Jaber‐Hijazi, Rouven Arnold, Karthic Swaminathan, Kathryn L. Gilroy, Alexander T. Wenzel, Anthony B. Lagnado, Kristina Kirschner, Neil Robertson, Claire Reid, Neil J. Fullarton, Jeff S. Pawlikowski, Taranjit Singh, Ian J Baranyk, Christina Huan Shi, Kevin Yuk-Lap Yip, , Peter D. Adams
This study shows that inactivating HIRA during embryonic development affects melanoblasts and leads to aging-related defects in melanocyte stem cells, but not in postnatal melanocytes.
Aging Cell · May 14, 2025Peer-reviewedDevelopmental Biology