Author

Nicholas Essepian

University of Virginia

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Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alev ErişiriD· 1 shared Eliana Sherman· 1 shared Lulu JiangiD· 1 shared Qingbo WangiD· 1 shared Rebecca Roberts· 1 shared Shuo Yuan· 1 shared Weronika GniadzikiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

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1 paper

Recent·Most cited

Tau Oligomerization Drives Neurodegeneration via Nuclear Membrane Invagination and Lamin B Receptor Binding in Alzheimer's disease

Nicholas Essepian, Shuo Yuan, Rebecca Roberts, Eliana Sherman, Weronika Gniadzik, Qingbo Wang, Alev Erişir, Lulu Jiang

This study shows that tau oligomerization causes nuclear membrane invagination and lamina disruption in Alzheimer's disease, linking nuclear stress to neurodegeneration.

bioRxiv · May 21, 2025 · PreprintNeuroscience