Alev Erişir

The paper develops a 3D brain assembloid model to study Alzheimer's disease progression and identifies IGFBP pathways as therapeutic targets in APOE4 carriers.

The paper compares the molecular and cellular organization of the superior colliculus across species, identifying conserved neuronal subtypes and synaptic genes while highlighting divergent ciliary genes and an inhibitory neuron subtype.

This study shows that tau oligomerization causes nuclear membrane invagination and lamina disruption in Alzheimer's disease, linking nuclear stress to neurodegeneration.

The paper shows that zebra finch auditory cortex neurons can rapidly change firing dynamics during a critical period for song learning, dependent on activity and involving Kv1.1 channel mobilization.

This study uses electron microscopy to show that synaptic spinules in ferret visual cortex increase in prevalence with age, mostly originating from postsynaptic spines and adjacent boutons, and are not correlated with sensory activity or plasticity onset.