Author

Nickolas Borowski

University of Massachusetts Amherst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Andrew D. StephensiD· 3 shared Andy Li· 2 shared Kelsey PrinceiD· 2 shared Adelaide S CutleriD· 1 shared Adriana G Panagiotou· 1 shared Allen Saini· 1 shared Antonela LosadaiD· 1 shared Bailey Lapolla· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCell Biology

Andrew D. StephensORCID

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3 papers

Recent·Most cited

Transcriptional activity generates chromatin motion that drives nuclear blebbing

Kelsey Prince, Nickolas Borowski, Katie Lin, Andy Li, Andrew D. Stephens

The paper shows that transcriptional activity drives chromatin motion, which causes nuclear blebbing, independent of nuclear mechanics or actin antagonism.

Molecular Biology of the Cell · Sep 16, 2026Peer-reviewedCell Biology

Nuclear blebs are composed of variable chromatin states but consistently enrich transcription initiation relative to elongation

Madeleine E Clark, Antonela Losada, Sonia E Jahng, Allen Saini, Fawwaz A Chowhan, Gwyneth L Woods, Adelaide S Cutler, Stephanie A Hallerman, Minnah A Gayed, Sayali Bhalerao, Emanuel Bullock, Chris Santry, Adriana G Panagiotou, Bailey Lapolla, Nitish Bhatta, , Andrew D. Stephens

The paper examines chromatin states and transcription dynamics in nuclear blebs, finding variable chromatin states but consistent enrichment of transcription initiation over elongation.

bioRxiv · Mar 11, 2026 · PreprintCell Biology

Topoisomerase I inhibition suppresses nuclear blebbing via RNA Pol II stalling and nuclear stiffening

Nickolas Borowski, Andy Li, Andrew D. Stephens

The paper shows camptothecin suppresses nuclear blebbing by stalling RNA Pol II and increasing chromatin stiffness.

bioRxiv · Jan 10, 2026 · PreprintCell Biology