Variation of human neural stem cells generating organizer states in vitro before committing to cortical excitatory or inhibitory neuronal fates
Nicola Micali, Suel–Kee Kim, Marcelo Diaz-Bustamante, Genevieve Stein-O’Brien, Seungmae Seo, Joo Heon Shin, Brian G. Rash, Shaojie Ma, Yanhong Wang, Nicolas A. Olivares, Jon I. Arellano, Kristen R. Maynard, Elana Judith Fertig, Alan J. Cross, Roland W. Bürli, , Ronald D.G. McKay
The paper models the progression of human neural stem cells in vitro, showing they transition through organizer states before committing to cortical excitatory or inhibitory neuronal fates.
Cell Reports · May 1, 2020Peer-reviewedNeuroscience