Author

Nicolas Fadell

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Aleksei Chekodanov· 1 shared Björn C. KnollmanniD· 1 shared Christopher N. JohnsoniD· 1 shared Daniel J. BlackwelliD· 1 shared Jonathan P. DavisiD· 1 shared Md Nure Alam AfsariD· 1 shared Melanie L. Aprahamian· 1 shared Peter Michael Kekenes-HuskeyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Aleksei Chekodanov

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1 paper

Recent·Most cited

Dynamic-Structure Redesign of Calmodulin Reveals Mechanistic Constraints on Ryr2 Regulation

Vladimir Bogdanov, Svetlana B. Tikunova, Nicolas Fadell, Robyn T. Rebbeck, Melanie L. Aprahamian, Md Nure Alam Afsar, Aleksei Chekodanov, Daniel J. Blackwell, Björn C. Knollmann, Rǎzvan L. Cornea, Peter Michael Kekenes-Huskey, Steffen Lindert, Christopher N. Johnson, Sándor Györke, Jonathan P. Davis

The paper redesigns calmodulin to improve its function while preserving conformational dynamics, showing that structural flexibility is essential for physiological regulation.

bioRxiv · Apr 17, 2026 · PreprintBiophysics