Gut Bacteria Prime Host Antibody Responses Against Ingested Dietary Fiber Glycans
Giovanni Vega, Carolina Agudelo, Meghan E. Graham, Elyza A. Do, Jasmin Akter, Rashidul Haque, Nicolette Hernandez-Kaempf, Khurshid R. Iranpur, Abigail Renfro, Ansel Hsiao, Ashley R. Wolf, Michael L. Patnode
The paper shows that dietary fiber glycans induce anti-fiber antibodies in humans and mice through microbial colonization, highlighting a role for gut bacteria in shaping host immune responses.
bioRxiv · Aug 17, 2026 · PreprintImmunology