Carolina Agudelo

This study identifies factors by which Mycobacterium tuberculosis suppresses Th17 responses during infection, showing that ESX-1 and PDIM inhibit IL-23 production in dendritic cells.

The paper shows that dietary fiber glycans induce anti-fiber antibodies in humans and mice through microbial colonization, highlighting a role for gut bacteria in shaping host immune responses.

This study uses a gnotobiotic mouse model to show that gut microbiome diversity does not affect Mtb lung burden, though it alters immune responses.

This study shows that methylglyoxal, a byproduct of aerobic glycolysis in infected macrophages, acts as an antimicrobial effector that enhances host defense against bacterial pathogens.