Ansel Hsiao

Gut Bacteria Prime Host Antibody Responses Against Ingested Dietary Fiber Glycans

The paper shows that dietary fiber glycans induce anti-fiber antibodies in humans and mice through microbial colonization, highlighting a role for gut bacteria in shaping host immune responses.

Social and neuroendocrine phenotypes reprogrammed by endocrine-disrupting chemicals can be mitigated by Limosilactobacillus reuteri modulation of the gut microbiome-thyroid-oxytocin axis

This study shows that Limosilactobacillus reuteri supplementation mitigates PBDE-induced ASD-like social and neuroendocrine deficits in mice by modulating the gut microbiome-thyroid-oxytocin axis.

Allosteric Inhibition of NDM-1 by Thanatin Preserves the Di-Zinc Center While Restricting Dynamics

This paper reveals that Thanatin inhibits NDM-1 by preserving its zinc center while restricting dynamics, contrasting with zinc-displacement models and showing reduced bacterial viability.

Native metabolomics identifies pteridines as CutA ligands and modulators of copper binding

The paper identifies pteridines, including lumazine dehydroxyxanthopterin B2, as natural ligands of CutA that modulate copper binding and redox homeostasis in E. coli and Synechococcus elongatus.