Anti-inflammatory and pro-proliferative effects of fasudil in human trisomy 21 neural progenitor cells
Laura L. Baxter, Sarah E. Lee, Kevin A. Fuentes, Iman A Mosley, Jonathan D. Raymond, Fayçal Guedj, Di Zhou, Donna K. Slonim, Elliot J. Glotfelty, David Tweedie, Nigel H. Grieg, Diana W. Bianchi
This study evaluates fasudil's effects on trisomy 21 neural progenitor cells, showing increased proliferation and reduced inflammation.
bioRxiv · Mar 20, 2026 · PreprintPharmacology & Toxicology