Screening of a pooled library of chimeric antigen receptor T cells based on secretory function
Citradewi Soemardy, Anna Huo-Chang Mei, Rocío Castellanos-Rueda, Nikol Garcia Espinoza, Monika Kizerwetter, Jamie B. Spangler, Sai T. Reddy, Dino Di Carlo
This paper presents a nanovial-based platform for high-throughput functional screening of CAR T cell libraries, identifying CAR constructs with distinct secretion profiles over time.
bioRxiv · Jul 2, 2025 · PreprintBioengineering