Functionalizing hydrogel nanovials with vesicles mimicking antigen-presenting vesicles and cancer exosomes improves T cell capture and activation
Blade A. Olson, Michael Mellody, Citradewi Soemardy…·Stephen L. Mayo
Author
University of California, Los AngelesORCID 0009-0002-0267-1097Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Blade A. Olson, Michael Mellody, Citradewi Soemardy…·Stephen L. Mayo
Citradewi Soemardy, Yan-Ruide Li, Yichen Zhu…·Dino Di Carlo
This paper develops a nanovial-based platform to identify functional TCRs from unconventional T cells, isolating and validating five novel MAIT TCRs with antigen-specific activity.
Citradewi Soemardy, Anna Huo-Chang Mei, Rocío Castellanos-Rueda…·Dino Di Carlo
This paper presents a nanovial-based platform for high-throughput functional screening of CAR T cell libraries, identifying CAR constructs with distinct secretion profiles over time.
Adi Idris, Alicia M. Davis, Aroon Supramaniam…·Kevin V. Morris
This paper develops an siRNA-nanoparticle therapy targeting SARS-CoV-2 that reduces viral load and improves survival in mice.