Redox-dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D.E. Sewell, John Carroll, György Szabadkai, Angus J. Bain, Michael R. Duchen
This study identifies redox-dependent binding configurations of NAD(P)H in live cells using FLIM and modeling, revealing how redox states influence fluorescence decay.
FEBS Letters · Jul 25, 2025Peer-reviewedBiochemistry