John Carroll

The paper identifies mechanisms of mitochondrial streaming in oocytes, showing actin-driven and chromatin-associated pathways that pattern mitochondrial distribution.

This paper introduces Airy beam light sheet microscopy to image subcellular dynamics in large tissues with high spatial and temporal resolution across multiple organisms and biological processes.

This study identifies redox-dependent binding configurations of NAD(P)H in live cells using FLIM and modeling, revealing how redox states influence fluorescence decay.

This study shows that Drp1-mediated mitochondrial fragmentation ensures symmetric organelle partitioning and faithful chromosome segregation in mouse zygotes.

This study shows that deleting Katna1 in mouse oocytes reduces fertility, while Katnal1 deletion has no effect, with defects in MII spindle morphology and fertilization rates.

The paper identifies a transient period of PRC2 activity in mouse and human oocytes that represses developmental genes, with conservation in human germline but loss during early embryonic development.