Thomas S. Blacker

This study shows that targeting lysosomal pH with rapamycin or acidic nanoparticles restores mitochondrial function in GBA1-mutant Parkinson's disease neurons.

This study identifies redox-dependent binding configurations of NAD(P)H in live cells using FLIM and modeling, revealing how redox states influence fluorescence decay.

This study shows that the E134K mutation in SMN disrupts its interaction with GAR1, impairing phase separation and contributing to spinal muscular atrophy.

The paper shows that glucose metabolism and morphogen signaling interact to establish tonotopic identity in developing hair cells by altering metabolic gradients and morphogen signaling.