Set1-mediated histone H3K4 methylation is required for azole induction of the ergosterol biosynthesis genes and antifungal drug resistance in Candida glabrata.
Kortany Maree Baker, Smriti Hoda, Debasmita Saha, Justin B. Gregor, Livia Georgescu, Nina D. Serratore, Yueping Zhang, Lizhi Cheng, Nadia A. Lanman, Scott D. Briggs
This study shows that Set1-mediated histone H3K4 methylation is essential for azole-induced expression of ergosterol biosynthesis genes and antifungal drug resistance in C. glabrata.
Antimicrobial Agents and Chemotherapy · Apr 26, 2022Peer-reviewedGenetics