Scott D. Briggs

The paper identifies an injury-induced complement program in kidney cells that couples inflammation to metabolism and chromatin regulation, promoting maladaptive fibrosis.

This study identifies Zcf27 and Zcf4 as distinct regulators of ergosterol gene expression in C. glabrata, showing their roles in azole resistance and hypoxic adaptation.

This paper demonstrates the efficient use of auxin-inducible degradation systems in Candida pathogens for rapid protein inactivation.

This paper expands genetic manipulation tools in Candida species using CRISPR-Cas9 RNP with new drug resistance cassettes, enabling efficient gene deletions and epitope tagging in multiple fungal pathogens.

This paper shows that reducing Cdc14 phosphatase activity in Candida albicans impairs cell wall integrity, septation, hyphal differentiation, and virulence, making it a potential antifungal drug target.

This study shows that Set1-mediated histone H3K4 methylation is essential for azole-induced expression of ergosterol biosynthesis genes and antifungal drug resistance in C. glabrata.