USP14 regulates pS129 α-synuclein levels and oxidative stress in human SH-SY5Y dopaminergic cells
Vignesh Srinivasan, Rabah Soliymani, Larisa B. Ivanova, Ove Eriksson, Nina Peitsaro, Maciej M. Lalowski, Mati M. Karelson, Dan Lindholm
This study shows that USP14 regulates pS129 α-synuclein and oxidative stress in SH-SY5Y cells by affecting proteasome activity and reducing ROS.
bioRxiv · May 9, 2024 · PreprintNeuroscience