Author

Noah A. Zaitlen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 3 Assay:GWAS summary statistics· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:polygenic risk· 2 Research Focus:variant effect prediction· 2 Research Focus:fine-mapping· 1

Frequent Co-Authors

Alexander Gusev· 2 shared Alkes L. Price· 2 shared Benjamin M Neale· 2 shared Bjarni J. Vilhjálmsson· 2 shared Bogdan Pasaniuc· 2 shared Gaurav Bhatia· 2 shared Mark Daly· 2 shared Nick Patterson· 2 shared

Activity by Year

2015-2016 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Alexander Gusev

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Subtle stratification confounds estimates of heritability from rare variants

Gaurav Bhatia, Alexander Gusev, Po-Ru Loh, Hilary Finucane, Bjarni J. Vilhjálmsson, Stephan Ripke, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Shaun Purcell, Eli Stahl, Mark Daly, Teresa R de Candia, Sang Hong Lee, Benjamin M Neale, Matthew C. Keller, Noah A. Zaitlen, , Alkes L. Price

This study shows that subtle population stratification can confound heritability estimates from rare variants, even after standard corrections, suggesting the need for better stratification control in genetic studies.

bioRxiv · Apr 13, 2016 · PreprintGenetics

Mixed Model Association with Family-Biased Case-Control Ascertainment

Tristan Hayeck, Noah A. Zaitlen, Po-Ru Loh, Samuela Pollack, Alexander Gusev, Nick Patterson, Alkes L. Price

This paper introduces LT-Fam, a family-based association statistic that is robust to family-biased case-control ascertainment, showing improved calibration and power compared to existing methods.

bioRxiv · Apr 5, 2016 · PreprintGenetics

Haplotypes of common SNPs can explain missing heritability of complex diseases

Gaurav Bhatia, Alexander Gusev, Po-Ru Loh, Bjarni J. Vilhjálmsson, Stephan Ripke, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Shaun Purcell, Eli Stahl, Mark Daly, Teresa R de Candia, Kenneth S. Kendler, Michael C O’Donovan, Sang Hong Lee, Naomi R. Wray, Benjamin M Neale, , Alkes L. Price

The paper shows that haplotypes of common SNPs explain more heritability of complex diseases than individual SNPs alone.

bioRxiv · Jul 12, 2015 · PreprintGenetics