Author

Shaun Purcell

Primary ORCID profile (0000-0002-7402-5812 · 30 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Shaun PurcelliD30 papers · Brigham and Women's Hospital

Biology Disciplines

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Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Research Focus:polygenic risk· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander Gusev· 1 shared Alkes L. Price· 1 shared Benjamin M Neale· 1 shared Bjarni J. Vilhjálmsson· 1 shared Bogdan Pasaniuc· 1 shared Eli Stahl· 1 shared Gaurav Bhatia· 1 shared Hilary Finucane· 1 shared

Activity by Year

2016-2016 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Alexander Gusev

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1 paper

Recent·Most cited

Subtle stratification confounds estimates of heritability from rare variants

Gaurav Bhatia, Alexander Gusev, Po-Ru Loh, Hilary Finucane, Bjarni J. Vilhjálmsson, Stephan Ripke, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Shaun Purcell, Eli Stahl, Mark Daly, Teresa R de Candia, Sang Hong Lee, Benjamin M Neale, Matthew C. Keller, Noah A. Zaitlen, , Alkes L. Price

This study shows that subtle population stratification can confound heritability estimates from rare variants, even after standard corrections, suggesting the need for better stratification control in genetic studies.

bioRxiv · Apr 13, 2016 · PreprintGenetics