Teresa R de Candia

The paper shows that marker-based heritability estimators are biased under assortative mating and proposes corrected estimators for traits under equilibrium assortative mating.

The paper compares methods for estimating heritability and genetic architecture using whole genome data and finds that larger imputation panels improve accuracy of causal variant frequency estimates.

This paper estimates narrow-sense heritability using identity-by-descent information in unrelated individuals and finds that IBD-based methods can capture rare variant contributions but are affected by stratification.

This study shows that subtle population stratification can confound heritability estimates from rare variants, even after standard corrections, suggesting the need for better stratification control in genetic studies.

The paper shows that haplotypes of common SNPs explain more heritability of complex diseases than individual SNPs alone.

The paper analyzes the genetic architecture of schizophrenia and nine complex diseases using a fast variance components analysis, finding polygenic patterns and significant genetic correlations.