A Molecular Mechanism for Probabilistic Bet-hedging and its Role in Viral Latency
Sonali Chaturvedi, Jon Klein, Noam Vardi, Cynthia Bolovan‐Fritts, Marie Wolf, Kelvin H. Du, Luwanika Mlera, Meredith Calvert, Nathaniel J. Moorman, Felicia D. Goodrum, Bo Huang, Leor S. Weinberger
The paper identifies stochastic variability in viral tegument protein abundance as a mechanism for probabilistic bet hedging between viral replication and latency in herpesvirus.
Proceedings of the National Academy of Sciences · Jul 6, 2020Peer-reviewedMolecular Biology