Felicia D. Goodrum

This study identifies host DNA repair factors that enable antiviral nucleoside analog resistance by facilitating viral DNA synthesis in the presence of ganciclovir.

This paper identifies UL138 as a viral protein that modulates host DNA repair pathways to maintain viral genome integrity during replication.

This study shows HCMV increases phosphatidylcholine (PC) levels through de novo synthesis during early replication, independent of late gene expression.

The paper analyzes the transcriptional network of HCMV in latency by comparing gene expression with and without UL135 and UL138, revealing their roles in viral gene regulation and hematopoietic differentiation.

This study investigates the role of PCNA in HCMV replication, finding it restricts virus replication and contributes to genome diversity through separable PCNA-dependent and -independent mechanisms.

The paper identifies stochastic variability in viral tegument protein abundance as a mechanism for probabilistic bet hedging between viral replication and latency in herpesvirus.

This study identifies EGR1 as a key transcription factor regulated by EGFR signaling that promotes CMV latency by enhancing UL138 expression in CD34+ HPCs.