NeurosciencebioRxivPreprint
Expansion of the neocortex and protection from neurodegeneration by in vivo transient reprogramming
Y Shen, Sofía Zaballa, Xavier Bech…·D del Toro
This study shows that transient Yamanaka factor expression during development expands the neocortex and improves cognitive function in mice, while intermittent expression in adult neurons protects against Alzheimer's disease features.
4 citations