Albert Giralt

This study identifies a proliferative-to-quiescent switch in microglial development and links it to epigenetic regulation and phagocytic function.

This study identifies sex-dependent interferon signaling as a driver of female-biased Alzheimer's disease vulnerability, showing that targeting this pathway can reduce pathology and improve cognition in female mice.

This study examines PYK2 levels and effects of its restoration in the striatum of HD mouse models and human patients, finding reduced levels but only partial improvement in motor phenotypes.

The paper shows that reduced IKZF1 and IKZF2 in immune cells of schizophrenic patients leads to impaired neural circuits and schizophrenia-like symptoms in mice and human cell models.

This study investigates how direct and indirect striatal pathways from DLS and DMS contribute to motor symptoms in HD mice, finding that these pathways are dysfunctional in HD.

This study shows that operant training with highly palatable food alters translating mRNA in NAc D2 neurons and that Ncdn downregulation modulates satiety-sensitive feeding behavior.

This study shows that transient Yamanaka factor expression during development expands the neocortex and improves cognitive function in mice, while intermittent expression in adult neurons protects against Alzheimer's disease features.

This study investigates the effects of intermittent fasting on adult neural stem cells and neurogenesis in mice, finding no significant impact on NSC activation, maintenance, or neurogenesis.

The paper shows that Egr1-dependent hippocampal neuronal ensembles limit motor learning in mice.

The paper identifies translational and splicing differences in dopaminoceptive neurons and highlights PGE2's role in enhancing D2 dopamine receptor function in the dorsal striatum.

This study shows that Pyk2 in D1 receptor-expressing neurons of the nucleus accumbens modulates acute cocaine-induced locomotor responses but not sensitization or place preference.