β-endorphin primes NK cells and NK-derived Extracellular Vesicle to enhance anti-tumor cytotoxicity
Ofir Bar, Nofar Aharon, Muhammad Abu Ahmad, Ishai Luz, Olga Radinsky, Angel Porgador, Tomer Cooks
This study shows β-endorphin enhances NK cell cytotoxicity and EV-mediated anti-tumor activity by remodeling the cytotoxic secretome.
bioRxiv · Jul 31, 2026 · PreprintCancer Biology