NeurosciencebioRxivPreprint
Kv7.2 Loss-of-Function Causes Early Hyperexcitability and Network Remodeling
Nina Dirkx, Mark D. Kaji, Els De Vriendt…·Sarah Weckhuysen
This study shows that KCNQ2 loss-of-function causes early hyperexcitability and network remodeling in human neurons, with biphasic changes in function, gene expression, and structure.
DOI 10.1101/2025.07.22.664856