Postoperative Stress Accelerates Atherosclerosis through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport
Dominique M. Boucher, Victoria Lorant, Valérie Rochon, Abigail Carter, Cameron Stotts, My-Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David P. Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet
This study shows that postoperative stress impairs reverse cholesterol transport and accelerates atherosclerosis through inflammatory remodeling of HDL and foam cell apoptosis.
Advanced Science · Jan 30, 2026Peer-reviewedBiochemistry