NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma
K. Brennan, J. H. Shin, J. K. Tay, M. Prunello, A. Gentles, J. B. Sunwoo, O. Gevaert
This study identifies an NSD1-inactivated, DNA hypomethylated, immune cold subtype in lung and head and neck squamous cell carcinomas, linked to poor immune infiltration and potential immunotherapy resistance.
bioRxiv · Oct 20, 2017Cancer Biology