Author

J. B. Sunwoo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

J. H. Shin· 2 shared K. Brennan· 2 shared A. Gentles· 1 shared B. Bernard· 1 shared B. Carter· 1 shared C. Chen· 1 shared C. Kuo· 1 shared C. Sievers· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

J. H. Shin

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3 papers

Recent·Most cited

Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.

N. Nigam, B. Bernard, S. Kim, K. Burkitt, D. Tsai, Y. Robbins, C. Sievers, C. T. Allen, R. L. Bennett, T. T. Tettey, B. Carter, R. Bao, L. Rinaldi, M. W. Lingen, H. Sater, , V. Saloura

This study identifies SMYD3 as an epigenetic regulator that suppresses the intrinsic interferon response in HPV-negative HNSCC, offering a potential strategy to enhance immunotherapy response.

bioRxiv · Nov 4, 2022 · PreprintCancer Biology

High-resolution positron emission microscopy of patient-derived tumor organoids

S. Khan, J. H. Shin, V. Ferri, N. Cheng, J. E. Noel, C. Kuo, J. B. Sunwoo, G. Pratx

This paper develops a high-resolution microscopy method to image FDG in tumor organoids, mirroring clinical PET scans and predicting treatment response.

bioRxiv · Jul 28, 2020Cancer Biology

NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma

K. Brennan, J. H. Shin, J. K. Tay, M. Prunello, A. Gentles, J. B. Sunwoo, O. Gevaert

This study identifies an NSD1-inactivated, DNA hypomethylated, immune cold subtype in lung and head and neck squamous cell carcinomas, linked to poor immune infiltration and potential immunotherapy resistance.

bioRxiv · Oct 20, 2017Cancer Biology