Author

O. Gursky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

D. Peterle· 1 shared E. A. Bullitt· 1 shared E. Lewkowicz· 1 shared E. S. Klimtchuk· 1 shared J. R. Engen· 1 shared L. H. Connors· 1 shared M. J. Rynkiewicz· 1 shared M. N. Nakamura· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

D. Peterle

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Author profile →

2 papers

Recent·Most cited

Molecular modeling of apoE in complexes with Alzheimers amyloid-beta fibrils from human brain suggests a structural basis for apolipoprotein co-deposition with amyloids

E. Lewkowicz, M. N. Nakamura, M. J. Rynkiewicz, O. Gursky

The paper models apoE interactions with Alzheimer's amyloid-beta fibrils, showing conformational changes enable binding and suggesting a mechanism for apolipoprotein-amyloid co-deposition.

bioRxiv · Aug 4, 2023Biophysics

Role of Complementarity-Determining Regions 1 and 3 in Pathologic Amyloid Formation by Human Immunoglobulin κ1 Light Chains

E. S. Klimtchuk, D. Peterle, E. A. Bullitt, L. H. Connors, J. R. Engen, O. Gursky

This study investigates how mutations in CDR1 and CDR3 regions of human immunoglobulin κ1 light chains influence amyloid formation through structural and dynamic analyses.

bioRxiv · Feb 1, 2023Biochemistry