Author

O. Haapanen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 4 Assay:cryo-EM· 3 Approach:experimental assay· 3 Approach:mechanistic / dynamical model· 2 Organism:yeast· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

V. Sharma· 4 shared V. Zickermann· 3 shared J. Lasham· 2 shared W. Kühlbrandt· 2 shared A. Altmeyer· 1 shared A. Amunts· 1 shared A. Djurabekova· 1 shared A. Marechal· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersBiochemistry

V. Sharma

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4 papers

Recent·Most cited

Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex

A. Muhleip, R. K. Flygaard, O. Haapanen, R. Baradaran, T. Gruhl, V. Tobiasson, A. Marechal, V. Sharma, A. Amunts

The paper reveals the structural basis of mitochondrial membrane bending by the I-II-III2-IV2 supercomplex using cryo-EM and molecular dynamics simulations.

bioRxiv · Jun 26, 2022 · PreprintBiochemistry

Tunnel dynamics of quinone derivatives and its coupling to protein conformational rearrangements in respiratory complex I

J. Lasham, O. Haapanen, V. Zickermann, V. Sharma

The paper uses molecular dynamics simulations to study how quinone derivatives move through the Q tunnel in complex I and how this movement couples with protein conformational changes.

bioRxiv · Jun 21, 2022Biophysics

Ion transfer mechanisms in Mrp-type antiporters from high resolution cryoEM and molecular dynamics simulations

Y. Lee, O. Haapanen, A. Altmeyer, W. Kühlbrandt, V. Sharma, V. Zickermann

The paper determines the structure of an Mrp antiporter using cryo-EM and simulates its mechanism, revealing a histidine-switch critical for ion translocation.

bioRxiv · Jan 24, 2022Biochemistry

High-resolution structure and dynamics of mitochondrial complex I - insights into the proton pumping mechanism

K. Parey, J. Lasham, D. J. Mills, A. Djurabekova, O. Haapanen, E. Galemou Yoga, H. Xie, W. Kühlbrandt, V. Sharma, J. Vonck, V. Zickermann

The paper presents a high-resolution cryo-EM structure of mitochondrial complex I from Yarrowia lipolytica, revealing proton translocation pathways and conformational changes linked to proton pumping.

bioRxiv · Apr 16, 2021Biochemistry