Author

O. Hernandez-Alba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

S. Cianferani· 3 shared A. Beck· 1 shared A. Konijnenberg· 1 shared B. Charpentier· 1 shared E. Del Nero· 1 shared E. Desligniere· 1 shared E. Wagner-Rousset· 1 shared F. Jacob-Dubuisson· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiophysics

S. Cianferani

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3 papers

Recent·Most cited

Denaturing mass photometry for straightforward optimization of protein-protein cross-linking reactions at single-molecule level

H. Gizardin-Fredon, P. E. Santo, M.-E. Chagot, B. Charpentier, T. M. Bandeiras, X. Manival, O. Hernandez-Alba, S. Cianferani

This paper introduces denaturing mass photometry (dMP) for optimizing protein cross-linking reactions, offering faster and more accurate analysis than SDS-PAGE.

bioRxiv · May 30, 2023Biophysics

Large-scale conformational changes of FhaC provide insights into the two-partner secretion mechanism

G. Sicoli, A. Konijnenberg, J. Guerin, S. Hessmann, E. Del Nero, O. Hernandez-Alba, S. Lecher, G. Rouaut, L. Mueggenburg, H. Vezin, S. CIANFERANI, F. Sobott, R. Schneider, F. Jacob-Dubuisson

The paper investigates conformational changes in FhaC, a TpsB transporter, revealing how it facilitates protein secretion without external energy sources through intrinsic dynamics.

bioRxiv · Nov 9, 2021Biophysics

Middle-level IM-MS and CIU experiments for improved therapeutic immunoglobulin isotype fingerprinting

T. Botzanowski, O. HERNANDEZ-ALBA, M. Malissard, E. Wagner-Rousset, E. Desligniere, O. Colas, J.-F. Haeuw, A. Beck, S. CIANFERANI

This paper introduces middle-level IM-MS and CIU methods for improved mAb isotyping, showing better differentiation of IgG isotypes compared to intact-level analysis.

bioRxiv · Jan 20, 2020 · PreprintBiophysics