Author

O. Irazoqui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

H. K. Johansen· 1 shared I. Pogrebnyakov· 1 shared L. Goltermann· 1 shared P. Laborda· 1 shared R. La Rosa· 1 shared S. Molin· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

H. K. Johansen

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1 paper

Recent·Most cited

Macrolide resistance through uL4 and uL22 ribosomal mutations in Pseudomonas aeruginosa

L. Goltermann, P. Laborda, O. Irazoqui, I. Pogrebnyakov, S. Molin, H. K. Johansen, R. La Rosa

This study shows that macrolides are effective against Pseudomonas aeruginosa in airway infections but lead to resistance via uL4 and uL22 ribosomal mutations, requiring higher antibiotic concentrations and reducing bacterial fitness.

bioRxiv · Apr 11, 2024 · PreprintMicrobiology