O. J. Bryant

The distinct translational landscapes of Gram-positive and Gram-negative bacteria

This study compares translational mechanisms in Gram-negative Salmonella and Gram-positive Listeria, revealing distinct regulatory features affecting protein synthesis efficiency.

Regulation of bacterial Type III Secretion System export gate opening

This study identifies residues in the T3SS export gate that regulate its opening in response to substrate availability and shows that FlhA energizes gate opening via proton motive force.

Recognition of discrete export signals in flagellar subunits during bacterial Type III secretion

The paper identifies a second export signal in bacterial flagellar subunits and shows its hydrophobicity is key to export, with implications for export gate opening.

Chaperone mediated coupling of subunit availability to activation of flagellar Type III Secretion

The paper shows that flagellar export chaperones regulate FliJ activation of the export gate to prevent pmf dissipation when subunit cargo is unavailable.