Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells.
P. J. Hooikaas, H. G. J. Damstra, O. J. Gros, W. E. van Riel, M. Martin, Y. T. H. Smits, J. van Loosdregt, L. C. Kapitein, F. Berger, A. Akhmanova
This study shows that KIF21B limits microtubule growth to enable rapid centrosome polarization in T cells by inducing microtubule pausing and catastrophe.
bioRxiv · Aug 28, 2020Cell Biology