Author

O. Lemke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

M. Muelleder· 2 shared M. Ralser· 2 shared A. Zelezniak· 1 shared D. Ludwig· 1 shared F. Buric· 1 shared J. Muenzner· 1 shared J. Zrimec· 1 shared K. Textoris-Taube· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

M. Muelleder

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Author profile →

2 papers

Recent·Most cited

An INS-1 beta-cell proteome highlights the role of fatty acid biosynthesis in glucose-stimulated insulin secretion

N. Stremmel, O. Lemke, K. Textoris-Taube, D. Ludwig, M. Muelleder, J. Muenzner, M. Ralser

This study uses proteomics to analyze glucose-stimulated insulin secretion in rat beta cells, finding that fatty acid metabolism plays a key role in the process.

bioRxiv · Jul 12, 2024 · PreprintCell Biology

The amino acid sequence determines protein abundance through its conformational stability and reduced synthesis cost.

F. Buric, S. Viknander, X. Fu, O. Lemke, J. Zrimec, L. Szyrwiel, M. Muelleder, M. Ralser, A. Zelezniak

This study shows that amino acid sequences determine protein abundance by affecting conformational stability and synthesis cost, using deep learning and yeast experiments.

bioRxiv · Oct 2, 2023Evolutionary Biology