Author

M. Muelleder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:yeast· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M. Ralser· 5 shared L. Szyrwiel· 3 shared V. Demichev· 3 shared A. Zelezniak· 2 shared K. Textoris-Taube· 2 shared A. Biswas· 1 shared A. Chelur· 1 shared A. Foti· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersBiochemistry

M. Ralser

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Tyrosine halogenation converts α-defensins into potent immunomodulators

A. Foti, R. Hurwitz, K. Textoris-Taube, M. Muelleder, A. Biswas, P. Fahjen, M. Winkler, U. Abu Abed, D. Humme, S. Thee, A. Prasse, B. Seeliger, M. Ralser, A. Zychlinsky

The paper identifies that tyrosine halogenation of α-defensins by hypohalous acids converts them into immunomodulatory mediators, revealing a novel oxidative mechanism in neutrophil function.

bioRxiv · Nov 1, 2023 · PreprintImmunology

The amino acid sequence determines protein abundance through its conformational stability and reduced synthesis cost.

F. Buric, S. Viknander, X. Fu, O. Lemke, J. Zrimec, L. Szyrwiel, M. Muelleder, M. Ralser, A. Zelezniak

This study shows that amino acid sequences determine protein abundance by affecting conformational stability and synthesis cost, using deep learning and yeast experiments.

bioRxiv · Oct 2, 2023Evolutionary Biology

Speedy-PASEF: Analytical flow rate chromatography and trapped ion mobility for deep high-throughput proteomics

L. Szyrwiel, C. Gille, M. Muelleder, V. Demichev, M. Ralser

Speedy-PASEF enables fast, high-quality proteomic analysis using moderate sample amounts, demonstrating its utility in studying COVID-19 plasma proteomes.

bioRxiv · Feb 17, 2023 · PreprintBiochemistry

High-throughput proteomics of nanogram-scale samples with Zeno SWATH DIA

Z. Wang, M. Muelleder, I. Batruch, A. Chelur, K. Textoris-Taube, T. Schwecke, J. Hartl, J. Causon, J. Castro-Perez, V. Demichev, S. Tate, M. Ralser

This paper introduces Zeno SWATH, a high-throughput proteomics method that improves protein identification and quantification in small sample amounts using fast chromatography.

bioRxiv · Apr 14, 2022Biochemistry

Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan

C. Correia-Melo, S. Kamrad, C. B. Messner, R. Tengolics, L. Herrera-Dominguez, S. Townsend, M. T. Alam, A. Freiwald, K. Campbell, S. Aulakh, L. Szyrwiel, J. S. L. Yu, A. Zelezniak, V. Demichev, M. Muelleder, , M. Ralser

The paper shows that metabolite exchange between cells extends lifespan in yeast by creating a pro-survival metabolic environment.

bioRxiv · Mar 7, 2022Biochemistry